Case Studies
BestScientific's Experience and Equipment used to its potential
Best Scientific has been responsible for Optical and innovative Technology to enable research studies over the years. Here you will see examples of some of the most interesting and influential studies Best Scientific has carried out.
These Case Studies are here to represent the ability of what can be created by Best Scientific.
- Detecting vCJD prions
Southampton researchers develop novel method for detecting vCJD prions on surgical instruments
- Online Vision System with E Beam
Diamond Light Source using technology provided by Best Scientific to provide the first Online Vision System with E Beam.
Other Papers
Other case studies best scientific have been involved with.
- A rapid dual staining procedure for the quantitative discrimination of prion amyloid from tissues reveals how interactions between amyloid and lipids in tissue homogenates may hinder the detection of prions
Research carried out in association with products purchased from Best Scientific
- Comparative Study of Surgical Instruments from Sterile-Service Departments for Presence of Residual Gram-Negative Endotoxin and Proteinaceous Deposits
The ineffective cleaning of surgical instruments may be a vector for the transmission of hospital-acquired infections. The aim of this research was to investigate whether further decontamination procedures need to be instigated in sterile-service departments (SSDs) to reduce the risk of nosocomial illnesses, such as endotoxemia, sepsis, or iatrogenic Creutzfeldt-Jakob disease.
- Targeting Species-Specific Low-Affinity 16S rRNA Binding Sites by Using Peptide Nucleic Acids for Detection of Legionellae in Biofilms
Using fluorescence in situ hybridization to detect bacterial groups has several inherent limitations. DNA probes are generally used, targeting sites on the 16S rRNA. However, much of the 16S rRNA is highly conserved, with variable regions often located in inaccessible areas where secondary structures can restrict probe access. Here, we describe the use of peptide nucleic acid (PNA) probes as a superior alternative to DNA probes, especially when used for environmental samples.
- Rapid detection of biofilms and adherent pathogens using scanning confocal laser microscopy and episcopic differential interference contrast microscopy.
Environmental Health Unit, School of Biological Sciences, University of Southampton.
- The sensitivity of approved Ninhydrin and Biuret tests in the assessment of protein contamination on surgical steel as an aid to prevent iatrogenic prion transmission.
Environmental Healthcare Unit, School of Biological Sciences, University of Southampton.
- Rapid method for the sensitive detection of protein contamination on surgical instruments.
Environmental Healthcare Unit, School of Biological Sciences, University of Southampton.
- Establishment of a continuous model system to study Helicobacter pylori survival in portable water biofilms.
Environmental Healthcare Unit, School of Biological Sciences, University of Southampton.
- Potential use of copper surfaces to reduce
survival of epidemic meticillin-resistant Staphylococcus aureus in the healthcare environment.
Environmental Healthcare Unit, School of Biological Sciences, University of Southampton.